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REDEFINE 1 trial highlights include: Additional phase 3 data from REDEFINE 1 included analyses exploring the cardiovascular risk reduction potential of investigational CagriSema and examining the percentage of people treated with CagriSema who achieved clinically relevant treatment targets for obesity management
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We further removed the GSA linker residues and found that a single GSA with two additional EF residues from the Eco RI cloning site is sufficient to activate the C347K mutant receptor at 30% of the activity of full-length peptide fusion receptor (Figure 5c, expression levels shown in Supplementary Figure S2A)
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